Date: Thu, 31 Jul 1997 12:10:47 GMT
From: (Ron Hoggan)
Subject: Re: seizures

On Wed, 30 Jul 1997 19:33:10 -0700, Linda  wrote:

>My four year old daughter had a seizure episode about six weeks ago. 

Hi Linda, 
I would like to suggest that you consider getting her tested for celiac
disease. There is an associated epilepsy that, if caught quickly, will
completely resolve on appropriate treatment of celiac disease...... a
gluten-free diet. 

Many cases are not caught very quickly, as celiac disease is taught as a
gastrointestinal disease, not a neurological one. I will append some
references. Blood testing at her age is not as accurate as it is for older
kids or adults, so the endoscopic biopsy is the best bet. 

Of course, she may not have celiac disease. But if there is a chance for
her to experience total recovery, I think it is a possibility worth
investigating. As you can see from the dates of the reports, knowledge of
the association is very new.  

I hope that is helpful. 

Best Wishes,
Ron Hoggan

1. Toti P, "Celiac disease with cerebral calcium and silica deposits: x-ray
spectroscopic findings, an autopsy study" _Neurology_ 1996; 46(4):

2. Baquero M, "Celiac disease with occipital calcifications: 2 late cases" 
_Med Clin_ (Barc) 1995; 105(20): 781-783 

3. Bhatia KP, "Progressive myoclonic ataxia associated with coeliac
disease. The myoclonus is of cortical origin, but the pathology is in the
cerebellum" _Brain_ 1995; 118( Pt 5):  1087-1093 

4. Lea ME, "Bilateral occipital calcification associated with celiac
disease, folate deficiency, and epilepsy" _AJNR Am J Neuroradiol_ 1995;
16(7): 1498-1500 (1995) 

5. Nunes ML, "Early onset bilateral calcifications and epilepsy" _Pediatr
Neurol_ 1995; 13(1): 80-82  

6. Cernibori A, "Partial seizures, cerebral calcifications and celiac
disease" _Ital J Neurol Sci_ 1995; 16(3): 187-191  

7. Fois A, "Celiac disease and epilepsy in pediatric patients" _Childs Nerv
Syst_ 1994; 10(7): 450-454  

8. Cohen O, "Convulsive disorder in celiac disease" _Harefuah_ 1994;
126(12): 707-710 

9. Magaudda A, "Bilateral occipital calcification, epilepsy and coeliac
disease: clinical and neuroimaging features of a new syndrome" _J Neurol
Neurosurg Psychiatry_ 1993; 56(8): 885-889 

10. Ambrosetto G, "Occipital lobe seizures related to clinically
asymptomatic celiac disease in adulthood"  _Epilepsia_ 1992; 33(3): 476-481

11. Della Cella G, "Intracranial calcifications--seizures--celiac disease:
a case presentation" _Pediatr Med Chir_ 1991; 13(4): 427-430 

12. Salvatoni A, "Hyponatremia and seizures during desmopressin acetate
treatment in hypothyroidism" _J Pediatr_ 1990; 116(5): 835-836 

13. Molteni N, "Celiac disease associated with epilepsy and intracranial
calcifications: report of two patients" _Am J Gastroenterol_ 1988;  83(9):

14/ Rush PJ, "Isolated vasculitis of the central nervous system in a
patient with celiac disease" _Am J Med_ 1986; 81(6): 1092-1094